Shahrekord University of Medical Sciences Epidemiology and Health System Journal 2980-7891 9 4 2022 11 05 Antimicrobial Resistance Pattern of Escherichia Coli Isolated From Patients With Urinary Tract Infection in Tehran, Iran, in 2021 160 163 10.34172/EHSJ.2022.29 EN Saied Bokaie https://orcid.org/0000-0003-3505-0270 Aliasghar Fakhri Demeshghieh https://orcid.org/0000-0003-1693-533X Ehsan Mosa Farkhani https://orcid.org/0000-0002-0474-5611 Abolghasem Shokri https://orcid.org/0000-0002-5895-6107 Journal Article 10.34172/EHSJ.2022.29 2022 04 29 2022 08 23 Background and aims: Urinary tract infections (UTIs) are intense public health problems and are precipitated by a variety of pathogens. This study was performed to determine the frequency of bacterial agents of UTIs and the antibiotic resistance pattern of Escherichia coli in urinary culture samples of patients at Shahid Ashrafi Esfahani hospital in Tehran, Iran. Methods: A cross-sectional study was conducted on all urinary tract cultures from January 2021 to January 2022 at Shahid Ashrafi Esfahani hospital in Tehran, Iran. Urine culture and antimicrobial susceptibility tests were performed according to Clinical and Laboratory Standards Institute (CLSI) guidelines. Statistical analyses were performed by appropriate descriptive and inferential tests such as the chi-square test using Stata version 17, and the level of significance was set at 0.05. Results: The mean age of patients with E. coli was 50.2±1.8 (confidence interval=46.6-53.8) years, and their age range was between 6-87 years. The highest prevalence of infection occurred in men over 60 years of age and in women aged 40-60 years. Further, the highest resistance and the highest sensitivity were related to ceftazidime (CAZ) and cefotaxime (CTX), respectively. Conclusion: In this study, the highest resistance and sensitivity belonged to CAZ and CTX, respectively. In addition, CTX is the primary antibiotic prescribed to deal with UTIs in medical practice.