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Int J Epidemiol Res. 2019;6(3): 120-127.
doi: 10.15171/ijer.2019.22
  Abstract View: 319
  PDF Download: 286

Original Article

A Case-Control Study of Timely Control and Investigation of an Entamoeba Histolytica Outbreak by Primary Health Care in Idahluy-e Bozorg Village, Iran

Hosein Azizi 1,2* ORCID logo, Elham Davtalab-Esmaeili 2 ORCID logo, Mohammad Mirzapour 3, Golamali Karimi 4 ORCID logo, Mahdi Rostampour 5 ORCID logo, Yagoob Mirzaei 6

1 Ph.D. Candidate in Epidemiology, Department of Epidemiology and Biostatistics, School of Health, Tehran University of Medical Sciences, Tehran, Iran.
2 Research Center of Psychiatry and Behavioral Sciences, Tabriz University of Medical Sciences, Tabriz, Iran
3 MD, Research Center of Psychiatry and Behavioral Sciences, Tabriz University of Medical Sciences, Tabriz, Iran
4 Research Center of Psychiatry and Behavioral Sciences, Tabriz University of Medical Sciences, Tabriz, Iran
5 Department of Disease Control and Prevention, Tabriz University of Medical Sciences, Malekan, Iran
6 Department of Communicable Disease, Tabriz University of Medical Sciences, Tabriz, Iran
*Corresponding Author: Hosein Azizi, Telefax: +984133826512 Email: , Email: epid_azizi@yahoo.com

Abstract

Background and aims: Experience transfer and the knowledge utilization of rapid and timely outbreak control can be the key path-finding to health systems (HSs). The aim of this study was to investigate an Entamoeba histolytica diarrhea outbreak through timely control.

Methods: A case-control study and an environmental survey were conducted to identify the source of infection and the outbreak etiological agent. Sixty-two confirmed cases in Idahluye Bozorg village, Iran, and 62 group-matched controls (in terms of age and sex) were selected from the healthy neighbors of the same village during the same period. Then, multiple logistic regression was applied to calculate the adjusted odds ratio for diarrhea risk.

Results: Totally, 250 cases were identified by a continuous common source epidemic from January 19th to 31st, 2018. Out of the total 36 stool samples, E. histolytica was detected as the common organism. In addition, the final analysis indicated that network drinking water (NDW) increased the odds of diarrhea (16.56, 95% CI=4.14-64.87), whereas well water and boiling water had protective effects and decreased the odds of diarrhea by 81% and 66%, respectively.

Conclusion: Overall, the source of infection was detected due to the contamination of underground NDW by pipe sewage erosion. Therefore, additional monitoring of water systems is necessary, especially during the summer and regarding full readiness for outbreak control.

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Submitted: 15 Feb 2019
Accepted: 28 Jul 2019
ePublished: 25 Sep 2019
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