Abstract
Zika virus is an Arbovirus identified first time in 1947 in Uganda. Zika epidemic is a threat far greater than the Ebola outbreak. The World Health Organization has urged Asian countries to be vigilant about the risk of spreading Zika virus and preventive measures to control it. In Iran, 64 species of mosquitoes from Culicidea family have been reported three of which belong to the Aedes genus, and one of which is Aedes albopictus. Iran also has suitable climate for endemic transmission of Zika virus. Immigrants from neighboring countries for economic reasons, could increase the risk of disease transmission in Iran. The destination countries of Iranian passengers, especially in East Asia, are at risk or have been reported to have cases of Zika. So, traveling to areas where active Zika virus exists and its transmission is common, could potentially increase the risk of transmission of Zika. Close supervision alongside the borders is necessary when foreign people arrive in the country.